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Evidence-Based Practice


3 Essential Elements
Evidence-Based Practice

EVIDENCE derived through rigorous scientific research.

EXPERTISE derived from the healthcare practitioner's clinical experience.

PATIENT preferences concerning personal healthcare decisions.

What Is EBP?

Evidence-Based Practice


A way of providing health care that is guided by a thoughtful integration of the best available scientific knowledge with clinical expertise. This approach allows the practitioner to critically assess research data, clinical guidelines, and other information resources in order to correctly identify the clinical problem, apply the most high-quality intervention, and re-evaluate the outcome for future improvement. (PubMed MeSH)

MeSH On Demand

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MeSH on Demand

Get help identifying MeSH terms for a comprehensive, high-quality search.

1. Go to MeSH on Demand

2. Copy/Paste your article abstract into the textbox.

3. Click this button: Find MeSH Terms

4. Wait for processing. (30-45 seconds depending on length of abstract)

5. See list of MeSH terms to explore in order to find additional high-quality articles.

Building a P I C O Question

Levels of Evidence

EB Practitioners must determine the strength of the evidence they find in the literature. Systems for rating the strength of evidence vary widely.

Locate the Evidence

Evidence in literature can be found anywhere, but it is best to start in Library Databases.

Viva La Evidence

by James McCormack   (4min 19sec)

Locating Evidence using P I C O Questions

Locating evidence in literature depends upon asking an effective research question. Use the PICO mnemonic to build that question.


     P -- patient, population, participant
      I -- intervention, therapy
     C -- comparison  (not always required)
     O -- outcome

 4 Types of PICO Questions

     1. Diagnosis
     2. Prognosis
     3. Therapy
     4. Etiology



Diagnosis PICO:
In children with respiratory infection, is the respiratory rate as effective as chest x-ray in detecting pneumonia?

Prognosis PICO:
In premature infants (compared to full-term infants), what is the lifetime prevalence of hearing deficit?

Therapy PICO:
In patients with recurrent infection, do antibiotics, compared to no treatment, reduce recurrence rate?

Etiology PICO:
In post-menopausal women, does hormone replacement therapy increase the risk of breast cancer?

PICO for Mobile Devices

Search PICO from any Mobile Device

English / Non-English PubMed PICO & PICO Mobile

Search Medline / PubMed using PICO in the following languages: 

  • Arabic
  • Chinese         
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  • Finnish
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  • German
  • Italian
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  • English