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NIH's All of Us

Overview of the All of Us Research Program

The All of Us Research Program is part of an effort to advance individualized health care by enrolling one million or more participants to contribute their health data over many years. The program aims to reflect the diversity of the United States and to include participants from groups that have been underrepresented in health research in the past. The program is developing custom tools and software to help researchers analyze participant data while keeping information secure. Working together, All of Us researchers, partners, and participants aim to build a better future for health care. Learn more about All of Us.

What Is the All of Us Research Program?

The National Institutes of Health’s (NIH’s) All of Us Research Program is building one of the largest biomedical data resources of its kind with health data from a diverse group of participants across the United States, including people and communities who have been left out of medical research in the past. Data include biological factors and social determinants of health on a large, inclusive scale that tracks participants as they move, age, and grow (longitudinal study design).

Data sources include:

  • Electronic Health Records (EHR) standardized using the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM)
  • Biosamples and bioassays from blood, saliva, and/or urine samples
  • Survey responses on identities and backgrounds, overall health, lifestyles, medical histories, healthcare access, experiences with COVID-19, and more
  • Physical measurements when joining program
  • Heart rate, physical activity, and sleep as tracked by wearable devices

Goal of the All of Us Research Program

The goal of All of Us is to speed up health research discoveries, enabling new kinds of individualized health care. To make this possible, the program is building one of the world’s largest and most diverse databases for health research.