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Critical appraisal is the process of systematically examining research to objectively assess its validity, results, and relevance.
Regardless of what type of research you are assessing, It is always necessary to consider the following questions.
Burls, A. (2009). What is critical appraisal? In What Is This Series: Evidence-based medicine. Available online at What is Critical Appraisal?
Cochrane is an international network but with headquarters in the UK, it is registered as a not for profit organization. The link leads to their published chapter on critical appraisal. http://ph.cochrane.org/sites/ph.cochrane.org/files/public/uploads/Unit_Eight.pdf